Meanwhile, life expectancy in the U.S. also declined last year, which the CDC said was primarily due to COVID-19 and unintentional injuries — which include drug overdoses.
The official number of U.S. overdose deaths in 2021 was 106,699 — which was just about 16% higher than the nearly 92,000 overdose deaths in 2020, the CDC said.
Earlier, provisional data suggested more than 107,000 overdose deaths last year. A CDC spokesman said that the numbers may have changed as some additional death records have come in.
Also, provisional data includes all overdose deaths, while the final numbers are limited to U.S. residents, he noted.
FILE IMAGE - Purple flags on display in front of Brigham & Women's Hospital, meant to represent the thousands of lives lost to drug overdoses, on Oct. 28, 2021. (Photo by David L. Ryan/The Boston Globe via Getty Images)
US life expectancy dropped in 2021
Meanwhile, life expectancy in the U.S. fell to about 76 years, 5 months in 2021, a decrease of 0.6 years from 2020, the CDC’s National Center for Health Statistics said. It was the lowest recorded figure since 1996.
The report noted how the drop in life expectancy in 2021 was largely due to increases in death caused by COVID-19, unintentional injuries — which include drug overdoses — as well as "chronic liver disease and cirrhosis, suicide, and homicide."
It added that while the drop of 0.6 years was not insignificant, it was lower than the decline of 1.8 years from 2019 to 2020.
The death rate increased by 5.3%, from 835.4 deaths per 100,000 people in 2020 to 879.7 per 100,000 in 2021.
Top 10 leading causes of death in US
Out of the top 10 leading causes of death in 2021, nine causes remained the same as in 2020, the CDC report said.
Heart disease continued to be the leading cause of death, followed by cancer and COVID-19, according to the report.
Chronic liver disease and cirrhosis became the 9th leading cause of death in 2021, while influenza and pneumonia dropped from the list of 10 leading causes. The remaining leading causes in 2021 — unintentional injuries, stroke, chronic lower respiratory diseases, Alzheimer's disease, diabetes, and kidney disease — remained at the same ranks as in 2020, the CDC said.
This story was reported from Cincinnati. The Associated Press contributed.